| Объем | 100 мкл |
| Синонимы | BCL2-associated athanogene 3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O95817 |
| Иммуноген | Fusion protein of human BAG3 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:500-1:2000, IHC:1:15-1:50 |
| Примечание | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Cancer,Cell biology,Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA056537(BAG3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
 |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA056537(BAG3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
 |
Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: Mouse muscle tissue, K562 cells, Primary antibody: CSB-PA056537(BAG3 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
 |
| | |
Наименование: BAG3 Antibody.