BAX AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Apoptosis regulator BAX, membrane isoform alpha, BAXA, Bcl2-associated X protein, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q07812 | | Иммуноген | Synthesized peptide derived from human Bax. | | Источник | Rabbit | | Видовая специфичность | Human, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200 | | Примечание | Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<br/><br/>Francesca Andriani, J Natl Cancer Inst, Sep 2001, 93: 1314 - 1324.<br/>H Martinez-Valdez, J. Exp. Med., Mar 1996, 183: 971.<br/>Joslyn K. Brunelle, J. Biol. Chem., Feb 2004, 279: 4305 - 4312.<br/>Renren Wen, Mol. Cell. Biol., Jan 2001, 21: 678 - 689. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cell biology,Metabolism | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293 cells, using Bax antibody.
 | Immunohistochemical analysis of paraffin-embedded human brain tissue using Bax antibody.
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Наименование: BAX Antibody.