Объем | 100 мкл |
Синонимы | H4, H4/n, H4F2, H4FN, FO108 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P62805 |
Иммуноген | Peptide sequence around acetylation site of Lysine 5(S-G-R(p)-G-K) derived from Human Histone H4. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat, Monkey |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | <p>Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic acetylpeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific acetylpeptide. Non-acetyl specific antibodies were removed by chromatogramphy using non-acetylpeptide. |
Абревеатура | Acetyl-Lys5 |
Области исследований | Others |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COS-7 cells untreated or treated with TSA, using Histone H4 (Acetyl-Lys5) Antibody.
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