C3 AntibodyСпецификация| Объем | 50 мкг | | Синонимы | Complement C3 (HSE-MSF) [Cleaved into: Complement C3 beta chain, C3-beta-c (C3bc), Complement C3 alpha chain, C3a anaphylatoxin, Acylation stimulating protein (ASP) (C3adesArg), Complement C3b alpha' chain, Complement C3c alpha' chain fragment 1, Complement C3dg fragment, Complement C3g fragment, Complement C3d fragment, Complement C3f fragment, Complement C3c alpha' chain fragment 2], C3 | | Клональность | Polyclonal Antibody | | Организм | mouse | | uniprot | P01027 | | Иммуноген | Recombinant Mouse Complement C3 protein (1321-1663AA) | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, Recommended dilution: WB:1:1000-1:5000 | | Примечание | C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. The short isoform hasB-cell stimulatory activity. Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Области исследований | Immunology | | Ссылка на страницу на сайте производителя | ссылка | Western blot
All lanes: Complement C3 antibody at 20µg/ml + Human high value serumGoat polyclonal to rabbit IgG at 1/10000 dilution
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 187, 61 kDa
Observed band size: 187 kDa
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Наименование: C3 Antibody.