Объем | 100 мкл |
Синонимы | calcium channel, voltage-dependent, L type, alpha 1C subunit |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q13936 |
Иммуноген | Synthetic peptide of human CACNA1C |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Примечание | This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Neuroscience,Cancer,Cardiovascular,Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA145166(CACNA1C Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA145166(CACNA1C Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
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