Объем | 100 мкл |
Синонимы | CALR, CRP55, CRTC, Calreticulin precursor, ERp60 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P27797 |
Иммуноген | Synthesized peptide derived from internal of human CALR. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
Примечание | Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis By similarity.<br/><br/>McCauliffe D.P., J. Clin. Invest. 85:1379-1391(1990).<br/>Rokeach L.A., J. Immunol. 147:3031-3039(1991).<br/>McCauliffe D.P., J. Biol. Chem. 267:2557-2562(1992).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Tags & Cell Markers |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COS-7 cells, using CALR antibody.
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Immunohistochemistry analysis of paraffin-embedded human heart tissue using CALR antibody.
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Immunofluorescence analysis of NIH/3T3 cells, using CALR antibody.
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