BCAS4 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | breast carcinoma amplified sequence 4 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q8TDM0 | | Иммуноген | Synthetic peptide of human BCAS4 | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:15-1:50 | | Примечание | The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer. This 20q13 locus amplification is found in 12%–39% of primary breast tumors, which correlates with a 17q23 locus amplification that is found in 20% of primary breast tumors. The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells. Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies. BCAS4 is normally expressed in thymus, kidney, spleen, placenta and brain. There are three isoforms of BCAS4 which are produced as a result of alternative splicing events. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cancer | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA687646(BCAS4 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: BCAS4 Antibody.