BCL2A1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | BCL2-related protein A1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q16548 | Иммуноген | Fusion protein of human BCL2A1 | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 | Примечание | This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cell biology | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA561279(BCL2A1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
| Gel: 12%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: Mouse testis tissue, hela cells, Primary antibody: CSB-PA561279(BCL2A1 Antibody) at dilution 1/117, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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