| Объем | 100 мкл |
| Синонимы | Caspase recruitment domain-containing protein 11, CARD-containing MAGUK protein 3, Carma 1, CARD11, CARMA1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9BXL7 |
| Иммуноген | Synthesized peptide derived from internal of human CARD11. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.<br/><br/>Bertin J., J. Biol. Chem. 276:11877-11882(2001).<br/>Gaide O., FEBS Lett. 496:121-127(2001).<br/>Hillier L.W., Nature 424:157-164(2003).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Immunology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells, using CARD11 antibody.
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Наименование: CARD11 Antibody.