Объем | 100 мкл |
Синонимы | Bcl-2-like protein 12, Bcl2-L-12, Bcl-2-related proline-rich protein, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9HB09 |
Иммуноген | Synthesized peptide derived from internal of human BCL2L12. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.<br/><br/>Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].<br/>Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].<br/>Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Cell biology,Metabolism |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from CoLo cells, using BCL2L12 antibody.
|
| |