| Объем | 100 мкл |
| Синонимы | 15-hydroxyprostaglandin dehydrogenase [NADP+], 2, 9-reductase, carbonyl reductase (NADPH), carbonyl reductase (NADPH) 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P16152 |
| Иммуноген | Synthesized peptide derived from internal of human CBR1. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.<br/><br/>Wermuth B., J. Biol. Chem. 263:16185-16188(1988).<br/>Forrest G.L., Biochim. Biophys. Acta 1048:149-155(1990).<br/>Forrest G.L., Mol. Pharmacol. 40:502-507(1991).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cell biology,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, using CBR1 antibody.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CBR1 antibody.
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Наименование: CBR1 Antibody.