Объем | 100 мкл |
Синонимы | 3010002G07Rik, BRAP2, BRCA1 associated protein, EC 6.3.2., Galectin 2 binding protein, IMP, Impedes mitogenic signal propagation, Renal carcinoma antigen NY REN 63, RING finger protein 52, RNF52, zgc:92894. |
Видовая специфичность | Human |
Uniport ID | Q7Z569 |
Иммуноген | Purified recombinant human BRAP protein fragments expressed in E.coli. |
Источник | Mouse |
Видовая специфичность 1 | Human |
Применение | ELISA,WB,Recommended dilution:WB:1:500-1:5000 |
Примечание | Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport. |
Изотип | IgG1 |
Метод очистки | Affinity purified |
Коньюгат | Non-conjugated |
Буффер | Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Области исследований | Epigenetics and Nuclear Signaling,Signal transduction |
Станица на сайте производителя | ссылка |
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