| Объем | 100 мкл |
| Синонимы | CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276), CD276, B7H3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q5ZPR3 |
| Иммуноген | Recombinant Human CD276 antigen protein (29-200AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | CD276 antigen |
| Области исследований | Cancer, Immunology, Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: CD276 antibody at 0.48µg/ml
Lane 1: U251 whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: HepG2 whole cell lysate
Lane 4: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 58, 34, 53 kDa
Observed band size: 53 kDa
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Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA745871ESR1HU at dilution of 1:100
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Наименование: CD276 Antibody.