Объем | 100 мкл |
Синонимы | IL6DBP, CRP2, TCF5, LAP, NF-IL6 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P17676 |
Иммуноген | Peptide sequence around aa.336~340(E-P-L-L-A) derived from Human C/EBPb. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation<br/><br/>Buck M., Poli V., Hunter T., Chojkier M. Mol. Cell 8:807-816(2001)<br/>Gauci S., Helbig A.O., Slijper M., Krijgsveld J. Mohammed S.Anal. Chem. 81:4493-4501(2009)<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Others |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Rat brain, Mouse brain tissue and 293 cells using C/EBPb Antibody.
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