| Объем | 100 мкл |
| Синонимы | Cdk5 and Abl enzyme substrate 1, FLJ35924, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8TDN4 |
| Иммуноген | Synthesized peptide derived from internal of human Ik3-1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death By similarity.<br/><br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Nusbaum C., Nature 437:551-555(2005).<br/>Wu C.-L., Cancer Res. 61:7325-7332(2001).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from LOVO cells, using Ik3-1 antibody.
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Наименование: CABLES1 Antibody.