| Объем | 50 мкл |
| Синонимы | Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain), CCAR1, CARP1 DIS |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8IX12 |
| Иммуноген | Recombinant Human Cell division cycle and apoptosis regulator protein 1 protein (1-200AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
| Примечание | Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Epigenetics and Nuclear Signaling, Cancer, Cell biology, Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: CCAR1 antibody at 10µg/ml
Lane 1: Hela whole cell lysate
Lane 2: PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 133, 132 kDa
Observed band size: 133 kDa
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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA816898ESR1HU at dilution of 1:100
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Наименование: CCAR1 Antibody.