| Объем | 50 мкг |
| Синонимы | Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform), CFL1, CFL |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P23528 |
| Иммуноген | Recombinant Human Cofilin-1 protein (4-144AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC, IF, Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
| Примечание | Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Cofilin-1 |
| Области исследований | Neuroscience, Cancer, Cardiovascular, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA04709A0Rb at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA04709A0Rb at dilution of 1:100
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Immunofluorescent analysis of HepG2 cells using CSB-PA04709A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Наименование: CFL1 Antibody.