CACNA1C Antibody, Biotin conjugatedСпецификацияОбъем | 100 мкг | Синонимы | Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2), CACNA1C, CACH2 CACN2 CACNL1A1 CCHL1A1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q13936 | Иммуноген | Recombinant Human Voltage-dependent L-type calcium channel subunit alpha-1C protein (1755-1971AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1C subunit play an important role in excitation-contraction coupling in the heart. The various isoforms display marked differences in the sensitivity to DHP compounds. Binding of calmodulin or CABP1 at the same regulatory sites results in an opposit effects on the channel function. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Biotin | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | Voltage-dependent L-type calcium channel subunit alpha-1C | Области исследований | Neuroscience, Cancer, Cardiovascular, Metabolism, Signal transduction | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | CSB-PA615724LD01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: CACNA1C Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке). |
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