CASP14 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | caspase 14, apoptosis-related cysteine peptidase | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P31944 | | Иммуноген | Fusion protein of human CASP14 | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 | | Примечание | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Gel: 12%SDS-PAGE, Lysate: 40 ?g, Lane 1-4: Jurkat cells, A431 cells, A549 cells, A375 cells, Primary antibody: CSB-PA168017(CASP14 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Наименование: CASP14 Antibody.