CAV1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CAV, CAV1, MSTP085, VIP21, caveolae protein | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q03135 | | Иммуноген | Synthesized peptide derived from human Caveolin-1. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 | | Примечание | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity By similarity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.<br/><br/>Wei Zhang, J. Biol. Chem., Jun 2000, 275: 20717.<br/>Rosalia Mora, J. Biol. Chem., Sep 1999, 274: 25708.<br/>Isabella Parolini, J. Biol. Chem., Sep 1999, 274: 25718.<br/>Phuong U. Le, J. Biol. Chem., Jan 2002, 277: 3371 - 3379.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cardiovascular,Tags & Cell Markers,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunofluorescence analysis of HuvEc cells, using Caveolin-1 antibody.
 | Western blot analysis of extracts from HuvEc cells, using Caveolin-1 antibody.
 | Western blot analysis of extracts from HuvEc cells (Lane 2), colo cells (Lane 3) and JK cells (Lane 4), using Caveolin-1 antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: CAV1 Antibody.