CCNL1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Cyclin-L, CCNL1, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9UK58 | Иммуноген | Synthesized peptide derived from human Cyclin-L1. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | Примечание | Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.<br/><br/>A. Hamid Boulares, J. Biol. Chem., Aug 1999, 274: 22932. <br/>Alessandra Pagano, Am J Physiol Lung Cell Mol Physiol, Jun 2007, 10.1152.<br/>Mi Young Kim, Genes & Dev., Sep 2005, 19: 1951 - 1967. <br/>Silke S篓绠俿e, Nucleic Acids Res., Feb 2004, 32: 669 - 680. <br/><br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Cyclin-L1 antibody.
| Western blot analysis of extracts from HepG2 cells, using Cyclin-L1 antibody.
| Western blot analysis of extracts from HeLa cells (Lane 2), A549 cells (Lane 3) and HepG2 cells (Lane 4), using Cyclin-L1 antiobdy. The lane on the left is treated with systhesized peptide.
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