CAV1 Antibody, Biotin conjugatedСпецификация| Объем | 100 мкл | | Синонимы | Caveolin-1, CAV1, CAV | | Клональность | Polyclonal | | Организм | Human | | uniprot | Q03135 | | Иммуноген | Recombinant Human Caveolin-1 protein (26-43AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (PubMed: 25893292). Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (PubMed: 19262564). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Biotin | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen Affinity Purified | | Абревеатура | Caveolin-1 | | Области исследований | Cancer, Cardiovascular, Tags & Cell Markers, Metabolism, Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA004571OD01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: CAV1 Antibody, Biotin conjugated.
Примечание: дополнительная информация (на английском языке). |
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