Объем | 100 мкл |
Синонимы | FLJ25804, MGC129906, MGC129907, cell division cycle associated 2, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q69YH5 |
Иммуноген | Synthesized peptide derived from C-terminal of human CDCA2. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.<br/><br/>Walker M.G., Curr. Cancer Drug Targets 1:73-83(2001).<br/>Ota T., . Genet. 36:40-45(2004).<br/>Olsen J.V., Cell 127:635-648(2006).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Metabolism |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells, using CDCA2 antibody.
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