| Объем | 100 мкл |
| Синонимы | KIAA1774, KIAA1812 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9H251 |
| Иммуноген | Synthetic peptide corresponding to residues near the C terminal of human pan-cadherin |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Neuroscience,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/30.
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Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/30.
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Наименование: CDH23 Antibody.