Объем | 50 мкл |
Синонимы | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P42773 |
Иммуноген | Fusion protein of human CDKN2C |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Примечание | The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA075339(CDKN2C Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA075339(CDKN2C Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ?200)
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