Объем | 50 мкл |
Синонимы | v-crk avian sarcoma virus CT10 oncogene homolog |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P46108 |
Иммуноген | Fusion protein of human CRK |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Примечание | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cancer,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA223350(CRK Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
![](http://www.cusabio.cn/images/antibody/shgo/IHC/CSB-PA223350-P.jpg) |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA223350(CRK Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
![](http://www.cusabio.cn/images/antibody/shgo/IHC/CSB-PA223350-1-P.jpg) |
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