Объем | 100 мкл |
Синонимы | AGP/EBP, C/EBP beta, C/EBP-related protein 2, CCAAT/enhancer binding protein beta, CEBPB |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P17676 |
Иммуноген | Synthesized peptide derived from internal of human CEBPB. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Plays an important role in adipose tissue differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG) as well as other adipogenesis key player genes. Isoform 3:acts as a dominant negative through heterodimerization with isoform 2.<br/><br/>Akira S., EMBO J. 9:1897-1906(1990).<br/>Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).<br/>Deloukas P., Nature 414:865-871(2001). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Others |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using CEBPB antibody.
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