| Объем | 100 мкл |
| Синонимы | CENA, CENP-A, Centromere autoantigen A, Centromere protein A, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P49450 |
| Иммуноген | Synthesized peptide derived from internal of human CENPA. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).<br/><br/>Sullivan K.F., J. Cell Biol. 127:581-592(1994).<br/>Hillier L.W., Nature 434:724-731(2005).<br/>Shelby R.D., J. Cell Biol. 136:501-513(1997).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CENPA antibody.
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Наименование: CENPA Antibody.