CSNK2A1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | CKII, CK2A1, CSNK2A1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P68400 | Иммуноген | Peptide sequence around aa. 353~357 (C-S-G-I-S) derived from Human CK2a. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.<br/><br/>Keller D.M., Zeng X., et al., Mol. Cell 7:283-292(2001) <br/>Keller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213(2002)<br/>Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457(2005)<br/>Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684(2000) <br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Cell biology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot of CK2a(Phospho-Thr360/Ser362) antibody and CK2aantibody in vitro kinase assay. Both purified ERK2 and CK2 were used.
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