| Объем | 100 мкл |
| Синонимы | Catenin beta-1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P35222 |
| Иммуноген | Synthetic peptide corresponding to a region derived from 757-770 amino acids of Human Catenin beta-1 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:2000 |
| Примечание | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[ |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 0.7mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Affinity purification |
| Области исследований | Others |
| Ссылка на страницу на сайте производителя | ссылка |
Gel: 10%SDS-PAGELane1: Mouse brain tissue lysateLane2: Mouse lung tissue lysateLysates: 24 ug per lanePrimary antibody: 1/350 dilutionSecondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/5000 dilutionExposure time: 1 minute
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Наименование: CTNNB1 Antibody.