| Объем | 100 мкл |
| Синонимы | CAS, CATNS, CTD1, CTND1, Cadherin-associated Src substrate |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O60716 |
| Иммуноген | Synthesized non-phosphopeptide derived from human Catenin-δ1 around the phosphorylation site of tyrosine 228 (D-N-Y(p)-G-S). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway By similarity. Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.<br/><br/>Keirsebilck A., Genomics 50:129-146(1998).<br/>Nagase T., DNA Res. 4:141-150(1997).<br/>W.S., Sherwood J.K., Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human brain tissue using Catenin-?1 (Ab-228) antibody.
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Western blot analysis of extracts from HuvEc cells, using Catenin-?1 (Ab-228) antibody.
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Western blot analysis of extracts from 293 cells (Lane 2), using Catenin-?1 (Ab-228) antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: CTNND1 (Ab-228) Antibody.