Объем | 100 мкл |
Синонимы | CFL, CFL1, COF1, Cofilin, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P23528 |
Иммуноген | Peptide sequence around aa. 1~5 (M-A-S-G-V) derived from Human cofilin. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 |
Примечание | Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.<br/><br/>Kobayashi M, et al. (2006) EMBO J 25(4): 713-26.<br/>Wang Y, et al. (2005)Biol Chem 280(13): 12683-9.<br/>Smith-Beckerman DM, et al. (2005) Mol Cell Proteomics: 156-68. <br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Neuroscience,Cancer,Cardiovascular,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from MDA cells using cofilin(Ab-3) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using cofilin(Ab-3) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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