CDC42BPA AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CDC42 binding protein kinase alpha (DMPK-like), CDC42 binidng protein kinase beta, CDC42-binding protein kinase alpha, CDC42-binding protein kinase alpha (DMPK-like), CDC42BPA | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q5VT25 | | Иммуноген | Synthesized peptide derived from Internal of human MRCKa. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200 | | Примечание | Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates: PPP1R12A, LIMK1 and LIMK2. May play a role in TFRC-mediated iron uptake.<br/><br/>Wilkinson S., Nat. Cell Biol. 7:255-261(2005).<br/>Totoki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.<br/>Bechtel S., BMC Genomics 8:399-399(2007).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat/COLO205 cells, using MRCKa antibody.
 | | | |
Информация для заказа |
Наименование: CDC42BPA Antibody.