Объем | 50 мкл |
Синонимы | Cofilin-2 (Cofilin, muscle isoform), CFL2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9Y281 |
Иммуноген | Recombinant Human Cofilin-2 protein (1-166AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Примечание | Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3 (PubMed:19752190). It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Cofilin-2 |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: CFL2 antibody at 3.75µg/ml
Lane 1: Mouse brain tissue
Lane 2: Mouse liver tissue
Lane 3: Mouse lung tissue
Lane 4: LO2 whole cell lysate
Lane 5: Hela whole cell lysate
Lane 6: A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 19, 17 kDa
Observed band size: 19 kDa
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA005281ESR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA005281ESR1HU at dilution of 1:100
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