CYP1A1 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | cytochrome P450, family 1, subfamily A, polypeptide 1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P04798 | Иммуноген | Synthetic peptide of human CYP1A1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 | Примечание | This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane: Mouse lung tissue, Primary antibody: CSB-PA547732(CYP1A1 Antibody) at dilution 1/220, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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