| Объем | 100 мкл |
| Синонимы | 1,25-dihydroxyvitamin D, 24- hydroxylase, 24-OHase, 24-hydroxylase |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q07973 |
| Иммуноген | Synthesized peptide derived from internal of human Cytochrome P450 24A1. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and calcitriol (1-alpha,25-dihydroxyvitamin D3). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.<br/><br/>Chen K.-S., Proc. Natl. Acad. Sci. U.S.A. 90:4543-4547(1993).<br/>Deloukas P., Nature 414:865-871(2001).<br/>Chen K.-S., Biochim. Biophys. Acta 1263:1-9(1995).<br/><br/> <br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HUVEC cells, using Cytochrome P450 24A1 antibody.
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Наименование: CYP24A1 Antibody.