Объем | 100 мкл |
Синонимы | claudin 3 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O15551 |
Иммуноген | Synthetic peptide of human CLDN3 |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC,ELISA:1:1000-1:10000, WB:1:500-1:2000, IHC:1:25-1:100 |
Примечание | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cancer,Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA561954(CLDN3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA561954(CLDN3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Gel: 10%SDS-PAGE, Lysate: 30 ?g, Lane: Human colon cancer tissue, Primary antibody: CSB-PA561954(CLDN3 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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