Объем | 100 мкл |
Синонимы | C6ST, carbohydrate sulfotransferase 2, EC 2.8.2.-, galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2, GlcNAc6ST-1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9Y4C5 |
Иммуноген | Synthesized peptide derived from internal of human CHST2. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.<br/><br/>Uchimura K., J. Biochem. 124:670-678(1998).<br/>Li X., Genomics 55:345-347(1999).<br/>Sakaguchi H., Biochim. Biophys. Acta 1523:269-276(2000).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Tags & Cell Markers |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, A549 cells and COLO cells, using CHST2 antibody.
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