Объем | 50 мкл |
Синонимы | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9NXZ2 |
Иммуноген | Fusion protein of human DDX43 |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
Примечание | DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX43 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 43), also known as CT13 or HAGE, is a 648 amino acid protein that contains one KH domain, one helicase C-terminal domain and one helicase ATP-binding domain and belongs to the DEAD-box family. Expressed in testis and present at abnormally high levels in a variety of tumors, DDX43 is thought to function as an ATP-dependent RNA helicase that may play a role tumor transformation and metastasis. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA994119(DDX43 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: HepG2 cells, Primary antibody: CSB-PA994119(DDX43 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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