Объем | 50 мкл |
Синонимы | Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1), CLK1, CLK |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P49759 |
Иммуноген | Recombinant Human Dual specificity protein kinase CLK1 protein (1-130AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Примечание | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Dual specificity protein kinase CLK1 |
Области исследований | Epigenetics and Nuclear Signaling, Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: CLK1antibody at 3.07µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: U251 whole cell lysate
Lane 4: A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 58, 17, 62 kDa
Observed band size: 58 kDa
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA005557ESR2HU at dilution of 1:100
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