DHRS2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | dehydrogenase/reductase (SDR family) member 2, dehydrogenase/reductase SDR family member 2, HEP27, protein D, SDR25C1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q13268 | | Иммуноген | Synthesized peptide derived from internal of human DHRS2. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.<br/><br/>Gabrielli F., Eur. J. Biochem. 232:473-477(1995).<br/>Pellegrini S., Biochim. Biophys. Acta 1574:215-222(2002).<br/>Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from COLO cells, using DHRS2 antibody.
 | | | |
Информация для заказа |
Наименование: DHRS2 Antibody.