CNOT2 (Ab-101) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CCR4-associated factor 2, CCR4-NOT transcription complex subunit 2, CCR4-NOT transcription complex, subunit 2, CDC36 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9NZN8 | | Иммуноген | Synthesized non-phosphopeptide derived from human CNOT2 around the phosphorylation site of serine 101 (S-L-S(p)-Q-G). | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.<br/><br/>Albert T.K., Nucleic Acids Res. 28:809-817(2000).<br/>Zhang Q.-H., Genome Res. 10:1546-1560(2000).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Others | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2 cells, treated with starved (24hours), using CNOT2 (Ab-101) antibody.
 | | | |
Информация для заказа |
Наименование: CNOT2 (Ab-101) Antibody.