COPZ1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CGI-120, coatomer protein complex, subunit zeta 1, COPZ, zeta1-COP | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P61923 | | Иммуноген | Synthesized peptide derived from internal of human COPZ1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors By similarity.The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.<br/><br/>Futatsumori M., J. Biochem. 128:793-801(2000).<br/>Lai C.-H., Genome Res. 10:703-713(2000).<br/>Zhang Q.-H., Genome Res. 10:1546-1560(2000)<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells and COS cells, using COPZ1 antibody.
 | Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using COPZ1 antibody.
 | | | |
Информация для заказа |
Наименование: COPZ1 Antibody.