E2F4 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | E2F-4, p107/p130-binding protein, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q16254 | | Иммуноген | Synthesized peptide derived from human E2F4. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1.<br/><br/>Kathryn M. Kinross, Blood, Aug 2006, 108: 886 - 895.<br/>Dawei Wang, Mol. Cell. Biol., May 2000, 20: 3417 - 3424.<br/>Stephan P. Persengiev, Mol. Cell. Biol., Sep 1999, 19: 6048 - 6056.<br/>Stefan Gaubatz, Mol. Cell. Biol., Feb 2001, 21: 1384 - 1392.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using E2F4 antibody.
 | Western blot analysis of extracts from COS7 cells, using E2F4 antibody.
 | Western blot analysis of extracts from JK cells (Lane 2), using E2F4 antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: E2F4 Antibody.