Объем | 100 мкл |
Синонимы | PHLL1 |
Клональность | Polyclonal Antibody |
Организм | Mouse |
uniprot | Q16526 |
Иммуноген | Peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Human CRY1. |
Источник | Rabbit |
Видовая специфичность | Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | <p>Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL <br /><br />Morioka N,et al. (2010) J Pharmacol Sci.113(3):234-45. <br />Fonseca F,et al. (2010) Mol Diagn Ther.14(3):171-8. <br />Stratmann M,et al.(2010) Genes Dev.24(12):1317-28.</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Neuroscience,Cardiovascular |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from mouse brain tissue using CRY1 antibody.
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Western blot analysis of extracts from 293T cells and Rat testis tissue using CRY1 Antibody.
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