Объем | 100 мкл |
Синонимы | Ephrin-A2 [Precursor], EPH-related receptor tyrosine kinase ligand 6, LERK-6, HEK7-ligand, HEK7-L |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O43921 |
Иммуноген | Synthesized peptide derived from Internal of human EFNA2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis By similarity.<br/><br/>Cerretti D.P., Genomics 47:131-135(1998).<br/>Aasheim H.C., Biochem. Biophys. Res. Commun. 252:378-382(1998).<br/>Grimwood J., Nature 428:529-535(2004).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Neuroscience,Cardiovascular |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells and HeLa cells, using EFNA2 antibody.
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