EFNB3 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | EFL6, EPLG8, LERK8, Ephrin B3, LIGAND OF EPH-RELATED KINASE 8 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q15768 | | Иммуноген | Synthesized peptide derived from human Ephrin-B3. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons By similarity.<br/><br/>Mitsutoshi Nakada, Cancer Res., Sep 2006, 66: 8492 - 8500.<br/>Klas Kullander, Genes & Dev., Apr 2001, 15: 877.<br/>M. Douglas Benson, PNAS, Jul 2005, 102: 10694 - 10699.<br/>Stephanie R. Kadison, J. Neurosci., Aug 2006, 26: 8909 - 8914.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Cardiovascular | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from SKOV3 cells, using Ephrin-B3 antibody.
 | Immunohistochemical analysis of paraffin-embedded human brain tissue using Ephrin-B3 antibody.
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Наименование: EFNB3 Antibody.