| Объем | 100 мкл |
| Синонимы | E2AK3, EC 2.7.11.1, EIF2AK3, Eukaryotic translation initiation factor 2-alpha kinase 3 precursor, HsPEK |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NZJ5 |
| Иммуноген | Synthesized peptide derived from internal of human E2AK3. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
| Примечание | Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1) By similarity.<br/><br/>Sood R., Biochem. J. 346:281-293(2000).<br/>Delepine M., Nat. Genet. 25:406-409(2000).<br/>Shi Y., J. Biol. Chem. 274:5723-5730(1999).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells and HepG2 cells, using E2AK3 antibody.
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Immunofluorescence analysis of HepG2 cells, using E2AK3 antibody.
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Наименование: EIF2AK3 Antibody.