ELP2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | elongator acetyltransferase complex subunit 2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q6IA86 | | Иммуноген | Fusion protein of human ELP2 | | Источник | Rabbit | | Видовая специфичность | Human, Rat | | Применение | ELISA, IHC,ELISA:1:2000-1:10000, IHC:1:100-1:300 | | Примечание | One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain . A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions . StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA276963(ELP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA276963(ELP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
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Наименование: ELP2 Antibody.