Объем | 100 мкл |
Синонимы | CK1-alpha, CKI-alpha, CSNK1A1, Casein kinase I, alpha isoform |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P48729 |
Иммуноген | Synthesized peptide derived from internal of human CKI-alpha. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
Примечание | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.<br/><br/>Tapia C., FEBS Lett. 349:307-312(1994).<br/>Fish K.J., J. Biol. Chem. 270:14875-14883(1995).<br/>Liu C., Cell 108:837-847(2002). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Signal transduction,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, using CKI-? antibody.
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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using CKI-? antibody.
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Immunofluorescence analysis of HeLa cells, using CKI-? antibody.
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